Article Correctness Is Author's Responsibility: Timing of brain cell death uncovers a new target for Alzheimer’s treatment

(Tokyo Medical and Dental University) Alzheimer's disease affects millions of people worldwide and is characterized by neuron loss and beta-amyloid plaque formation in the brain. Researchers led by Tokyo Medical and Dental University have now found that neuron degeneration beings much earlier than originally thought and is dependent on a protein called YAP. Supplementation with a YAP analog restored cognitive function and prevented neuron loss in Alzheimer's disease mice, paving the way for novel human therapeutics.